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Research projects

Here you find the projects conducted by the research group Sport Performance and Exercise Research & Innovation Center-Stockholm, SPERIC-S.

Our projects

The list in the table consists of anchor links. Click on the project name if you are interested in reading more about the project. If you click on the researcher in charge you will be directed to their profile page.

Projects

Name of the project

Responsible researcher

Use of muscle fiber composition to identify early events in insulin resistance

Abram Katz

Use of xenotransfusion to evaluate the effects of training on multiple

Abram Katz

The Swedish Parasport Academy – a development environment for collaboration around physical activity and sports

Anna Bjerkefors and Yves Vanlandewijck

Development of a trunk multi-function test for seated Paralympic sport

Anna Bjerkefors and Yves Vanlandewijck

Activity breaks for brain health in wheelchair users (E-PABS)

Anna Bjerkefors

Riksidrottsuniversitet with dual careers

Dan Wiorek

GLIMPSE (Glucose, Immune function, Mitochondria, Performance and Sleep in Elite athletes)

Filip Larsen

Isothiocyantes and Metabolic Health

Filip Larsen

Nrf2-activation and adaptations to exercise training

Filip Larsen

Adaptive training

Filip Larsen

Validation and application of new methodology for power and force measurements in elite level sprint kayaking

Hans Rosdahl

Validity and reliability for determination of oxygen uptake with the Vyntus CPX Metabolic Cart

Hans Rosdahl

Concurrent training for well-trained team sport athletes

Henrik Petré

Explore sustainable high-performance coaching through the lens of self-compassion

Karin Hägglund

Cultural and organizational development of distance education at the GIH – KOD project

Kerstin Hamrin and Eva Fors

University pedagogy in teaching human biology

Kerstin Hamrin and Eva Fors

Knee biomechanics and sport – with emphasis on progression in rehabilitation and return to sport after knee injury

Jonas Enqvist

Tests of the physical ability of the rescue service

Lasse ten Siethoff

The potential role of lactate in the molecular regulation of muscle adaptations to exercise

Marcus Moberg

Lactate – a multi organ signaling molecule with important health implications

Marcus Moberg

The influence of hypoxia on the molecular response to resistance exercise

Marcus Moberg

Exercise neurophysiology – molecular regulation of BDNF production

Marcus Moberg

ExeRcise Intensity and Neuroplastcity (ERIN)

Marcus Moberg

Effect of intrasession exercise order of flywheel resistance and high-intensity interval training on maximal strength and power performance in highly trained team sport athletes

Niklas Psilander

The effect of different rest periods after endurance training on strength and power in female, elite ice-hockey players

Niklas Psilander

Myonuclear permanence in gastrocnemius muscle after Achilles tendon rupture

Niklas Psilander

Evidence for muscle memory by myonuclear permanence and transcriptional regulation in human muscle after strength training

Niklas Psilander

Molecular mechanisms underpinning anabolic resistance in sarcopenic obesity

Oscar Horwath

Molecular mechanisms for muscle growth in the fast and slow-twitch muscle fibers of the young and old

Sebastian Edman

Fast-twitch muscle fiber mitochondria favor power over efficiency

Sebastian Edman

Advanced Footwear Technology (AFT) shoe energy return protocol for potential integration in World Athletics rules for regulation

Toni Arndt

Individual runners’ characteristics and their correlation to performance enhancement in AFT shoes

Toni Arndt

One year longitudinal analysis of recreational runners’ use of different shoes and potential injury consequences

Toni Arndt

Triceps surae mechanics in people with leg spasticity

Toni Arndt

Achilles tendon internal displacement during running in minimalistic shoes

Toni Arndt

Biomechanical modelling of loading in knee structures as tool for guiding return to sports decisions in elite alpine skiers

Toni Arndt

Cognitive abilities under pressure/stress/crisis before and after exhaustion/physical exertion

Torbjörn Helge

Karolinska football Injury Cohort, KIC study

Ulrika Tranaeus

Climber's Longitudinal attitudes toward Injury, Mental health, and behaviours, CLIMB study

Ulrika Tranaeus

Long term Athlete Sustainable Sport Environment, LASSE

Ulrika Tranaeus

Transition from being a talented athletic youth athlete to an adult elite

Ulrika Tranaeus

Psychosocial factors associated with the recovery stages following sport-specific injuries at different levels of performance: A systematic review

Ulrika Tranaeus

From risk to return, a consensus project

Ulrika Tranaeus

Anabolic potential of skeletal muscle in healthy ageing

William Apró

Fiber type specific regulation of protein synthesis in young and elderly muscle

William Apró

Muscle protein breakdown and the role of glycogen availability and amino acid supplementation

William Apró

Fiber type specific cell-signalling responses to energy and nutrient availability

William Apró

Anabolic resistance in sarcopenia and obesity

William Apró

Towards an evidence-based and fair classification system for athletes with Cerebral Palsy

Yves Vanlandewijck

Use of muscle fiber composition to identify early events in insulin resistance

This study uses muscle fiber composition to follow the natural development of insulin resistance, a risk factor for obesity, type 2 diabetes, and hypertension. Early detection of insulin resistance is critical since it can be reversed by non-invasive approaches such as exercise and diet.

Responsible researcher

Abram Katz

Project period

2022–2023

Use of xenotransfusion to evaluate the effects of training on multiple

The transfusion of mice that will develop multiple sclerosis with plasma from trained and untrained humans will demonstrate whether exercise results in a blood-borne factor that affects disease progression. This may lead to the development of pharmacological agents to prevent or treat neuromuscular diseases.

Responsible researcher

Abram Katz

Project period

2022-2023

The Swedish Parasport Academy – a development environment for collaboration around physical activity and sports

The project aims to investigate how a neuromusculoskeletal disability affects activities in everyday life, physical activity in free time, and para-athletes. The results are expected to lead to an increased understanding of how function can be optimized with assistive devices based on the individual's needs and conditions and how the load on the shoulder or arm and seat can be minimized. The goal is to find the optimal level between function and performance for wheelchair users in everyday situations and from a sports performance perspective.

Responsible researchers

Anna Bjerkefors and Yves Vanlandewijck

Project period

2022–2026

Development of a trunk multi-function test for seated Paralympic sports

This project aims to develop and evaluate a non-sport-specific core test for assessing strength, active range of motion, and coordination in para-athletes. Creating such a test battery increases knowledge about how trunk function can be evaluated, contributing to a fairer classification of Paralympic athletes participating in seated Paralympic sports.

Responsible researchers

Anna Bjerkefors and Yves Vanlandewijck

Project period

2022–2025

Activity breaks for brain health in wheelchair users (E-PABS)

The project evaluates how certain types of physical activity can affect the brain health of wheelchair users who have a spinal cord injury and are physically inactive. Acute effects of performing activity breaks with specific exercises are evaluated on biochemical and cerebrovascular mechanisms.

Responsible researcher

Anna Bjerkefors

Project period

2023–2025

Riksidrottsuniversitet with dual careers

Riksidrottsuniversitetet with dual careers is aimed at you who are elite athletes and connected to RIU. As an RIU student, we work to facilitate your study time through flexible and adapted solutions that aim to create a good development environment with opportunities to pursue university studies in parallel with your sport. Riksidrottsförbundet, GIH, and KTH collaborate on this issue for RIU students at GIH and KTH.

Responsible researcher

Dan Wiorek

Project period

2022–2026

GLIMPSE (Glucose, Immune function, Mitochondria, Performance and Sleep in Elite athletes)

This project is a longitudinal study for one year where we follow elite athletes in their regular training and competition using wearable technologies. The aim is to find early signs of overtraining and optimize the training programs for better performance.

Responsible researcher

Filip Larsen

Project period

2021 – ongoing

Isothiocyantes and Metabolic Health

In this project, we investigate the effects of isothiocyanates in the kale family's vegetables. We look at how these compounds affect insulin sensitivity, inflammatory markers, and resistance to oxidative stress.

Responsible researcher

Filip Larsen

Project period

2022 – ongoing

Nrf2-activation and adaptations to exercise training

In this project, we are studying how supplementation with isothiocyanates and physical training affects the adaptation process on the mitochondrial and whole-body levels.

Responsible researcher

Filip Larsen

Project period

2020 – ongoing

Adaptive training

This project aims to use the knowledge gained in the GLIMPSE project to fine-tune the training load daily to optimize health outcomes and physical performance.

Responsible researcher

Filip Larsen

Project period

2023–2025

Validation and application of new methodology for power and force measurements in elite level sprint kayaking

The project aims to investigate whether new technology with new measurement variables for sprint canoeists can be used to monitor the intensity of the training and improve the efficiency of the canoeists.

Responsible researcher

Hans Rosdahl

Project period

2022–2023

Validity and reliability for determination of oxygen uptake with the Vyntus CPX Metabolic Cart

The purpose of this study is to evaluate a new measurement system, the Vyntus CPX Metabolic Cart, concerning its validity and reliability.

Responsible researcher

Hans Rosdahl

Project period

2022–2023

Concurrent training for well-trained team sport athletes

In the project, we investigate how variables linked to training design affect the effects of strength training during combination training in well-trained team athletes.

Responsible researcher

Henrik Petré

Project period

2019–2023

Explore sustainable high-performance coaching through the lens of self-compassion

The project aims to develop tools for sustainable leadership in elite sports. The research is based on self-compassion theory and is in collaboration with Riksidrottsförbundet.

Responsible researcher

Karin Hägglund

Project period

2022–2026

Cultural and organizational development of distance education at the GIH – KOD project

The project's purpose is to lay the foundation for the long-term cultural development of GIH's organization around distance education. Within the project, various proposals are being tested on how an adapted distance and hybrid-based study environment can be realized.

Responsible researchers

Kerstin Hamrin and Eva Fors

Project period

2022–2023

University pedagogy in teaching human biology

The project's goal is to develop our teaching in different ways, including finding out how the students think when they study and what kind of study patterns they have.

Responsible researchers

Kerstin Hamrin and Eva Fors

Project period

2021–2023

Knee biomechanics and sport – with emphasis on progression in rehabilitation and return to sport after knee injury

The project aims to increase knowledge about how external load is distributed in the various structures of the knee joint by creating a musculoskeletal model that non-invasively analyzes how knee load is affected by movement, load, muscular activation, and after a knee injury. The purpose is also to investigate how well self-assessed knee health relates to objective measures of knee function.

Responsible researcher

Jonas Enqvist

Project period

2021–2025

Tests of the physical ability of the rescue service

The project's mission is to review and find common grounds for tests and requirements concerning recruitment, consensus regarding annual physical tests, and a standard guideline for physical training.

Responsible researcher

Lasse ten Siethoff

Project period

2021–2022

The potential role of lactate in the molecular regulation of muscle adaptations to exercise

In this project, we have given young, healthy subjects a venous infusion of lactate or a placebo during strength training to artificially raise lactate levels during exercise. Blood and muscle samples were taken in conjunction with the intervention to study the potential effect of lactate on the exercise response.

Responsible researcher

Marcus Moberg

Project period

2018–2023

Lactate – a multi organ signaling molecule with important health implications

In this project, we give young, healthy subjects a venous infusion of lactate or placebo during complete rest. Blood samples, muscle samples, and adipose tissue samples are taken in connection with the intervention to study the horn-like effects of lactate in the brain, muscle, and adipose tissue.

Responsible researcher

Marcus Moberg

Project period

2022–2025

The influence of hypoxia on the molecular response to resistance exercise

In this project, healthy individuals were allowed to do strength training in normoxia (regular air) or hypoxia (simulated high altitude). Muscle samples were taken with the training to study the influence on the molecular response to training.

Responsible researcher

Marcus Moberg

Project period

2019–2023

Exercise neurophysiology – molecular regulation of BDNF production

This project collects data from several previous interventions to map which factors in the body control the effects of training on the neuronal growth factor BDNF.

Responsible researcher

Marcus Moberg

Project period

2020–2023

ExeRcise Intensity and Neuroplastcity (ERIN)

This project aims to map which molecular factors control the effects of training on neuroplasticity and primarily studies the impact of training intensity.

Responsible researcher

Marcus Moberg

Project period

2022–2025

Effect of intrasession exercise order of flywheel resistance and high-intensity interval training on maximal strength and power performance in highly trained team sport athletes

The project investigates how the strength and conditioning training sequence affects elite active athletes' (men) development of maximal strength jumping ability.

Responsible researcher

Niklas Psilander

Project period

2021–2023

The effect of different rest periods after endurance training on strength and power in female, elite ice-hockey players

The project examines how long the rest must be after a hard conditioning session for elite active hockey players (women) to regain maximum strength and jumping ability.

Responsible researcher

Niklas Psilander

Project period

2022–2023

Myonuclear permanence in gastrocnemius muscle after Achilles tendon rupture

The project investigates what happens to the cell nuclei of the calf muscles after the Achilles tendon ruptures and the muscle cannot be loaded for longer (men and women).

Responsible researcher

Niklas Psilander

Project period

2019–2023

Evidence for muscle memory by myonuclear permanence and transcriptional regulation in human muscle after strength training

The project investigates whether muscle memory is linked to cell nuclei in the arm muscles (men and women).

Responsible researcher

Niklas Psilander

Project period

2019–2023

Molecular mechanisms underpinning anabolic resistance in sarcopenic obesity

The project aims to understand more about how skeletal muscle is affected by aging and obesity. More specifically, the project will investigate which cellular and molecular factors in blood plasma and muscle tissue may be behind muscle loss in sarcopenic obesity.

Responsible researcher

Oscar Horwath

Project period

2022–2024

HEInnovaSport: Building innovation capacity and entrepreneurship in sport science

HEInnovasport is a knowledge and innovation collaboration project to promote innovation and entrepreneurship within the university, focusing on sports, health, and performance development.

Responsible researcher

Sofia Brorsson

Project period

2022–2024

Molecular mechanisms for muscle growth in the fast and slow-twitch muscle fibers of the young and old

Our fast and slow muscle fibers have different capacities for muscle growth and are affected very differently by aging. The purpose of this project is thus to investigate whether the molecular signaling pathways that control muscle growth are expressed differently in our fast and slow muscle fibers.

Responsible researcher

Sebastian Edman

Project period

2020–2023

Fast-twitch muscle fiber mitochondria favor power over efficiency

Studies on the mitochondrial population in our fast and slow muscle fibers have previously been methodologically limited. Still, thanks to our new method of fiber type identification, we can now study the mitochondria in living human muscle fibers for the first time. This has the potential to give us unique insights into how to exercise muscle activity affects human health and performance.

Responsible researcher

Sebastian Edman

Project period

2020–2023

Advanced Footwear Technology (AFT) shoe energy return protocol for potential integration in World Athletics rules for regulation

Shoes with AFT are mechanically tested and the research group at GIH in collaboration with KTH is suggesting implementation of this testing protocol in the regulation of shoes worn by elite athletes governed by World Athletics.

Responsible researcher

Toni Arndt

Project period

2019–2023

Individual runners’ characteristics and their correlation to performance enhancement in AFT shoes

Recent studies have shown an improved running economy when running in AFT shoes. However, there is a considerable spread in the runners' response to the shoes. This study will investigate anthropometric, strength, and biomechanical characteristics. The reason is to identify whether any runner-specific characteristics provide better prerequisites for some runners to be responders and gain more significant advantages from AFT shoes.

Responsible researcher

Toni Arndt

Project period

2019–2023

One year longitudinal analysis of recreational runners’ use of different shoes and potential injury consequences

In collaboration with Linköpings University we will follow over 300 recreational runners over one year with weekly follow-up in a phone app describing running volume, shoes worn, and injuries. This will be the first longitudinal study identifying whether AFT shoes may increase or decrease injury risks.

Responsible researcher

Toni Arndt

Project period

2022–2024

Triceps surae mechanics in people with leg spasticity

Collaboration project with KTH. Identifying biomechanical muscle function characteristics in stroke patients to assist in rehabilitation and supported living.

Responsible researcher

Toni Arndt

Project period

2019–2024

Achilles tendon internal displacement during running in minimalistic shoes

A continuation of previous Achilles tendon works with KTH and KI using the speckle tracking ultrasound method first used by this group already in 2012. An application to see whether barefoot running or minimalistic shoes may decrease non-homogenous displacement in the tendon and potentially expose it to significant risk of chronic and acute injury.

Responsible researcher

Toni Arndt

Project period

2017–2023

Biomechanical modelling of loading in knee structures as tool for guiding return to sports decisions in elite alpine skiers

The decision to return to elite alpine skiing after knee surgery is based on expert opinion from medical and training staff. This project intends to provide information on the load's knee structures. In particular, the anterior cruciate ligament is subjected to functional movements to guide the decision-making process with scientific data.

Responsible researcher

Toni Arndt

Project period

2021–2025

Cognitive abilities under pressure/stress/crisis before and after exhaustion/physical exertion

The study is designed to answer questions about how cognitive abilities are affected in the short term by stressful exercises in military training and which factors influence any changes. We primarily study the impact of commonly occurring elements in training and the more extreme exercise elements.

Responsible researcher

Torbjörn Helge

Project period

2021–2023

Karolinska football Injury Cohort, KIC study

This study aims to investigate risk factors for injuries in young soccer girls.

Responsible researcher

Ulrika Tranaeus

Project period

2022–2025

Climber's Longitudinal attitudes toward Injury, Mental health, and behaviours, CLIMB study

This study aims to investigate injuries and health as well as attitudes and behaviors regarding this in Swedish elite climbers.

Responsible researcher

Ulrika Tranaeus

Project period

2022–2026

Long term Athlete Sustainable Sport Environment, LASSE

This study aims to investigate the sports environment and health of Swedish athletes.

Responsible researcher

Ulrika Tranaeus

Project period

2022–2026

Transition from being a talented athletic youth athlete to an adult elite

This study aims to investigate, through interviews, the experiences, knowledge, and needs of high school athletics students regarding health and sports injuries.

Responsible researcher

Ulrika Tranaeus

Project period

2022–2025

Psychosocial factors associated with the recovery stages following sport-specific injuries at different levels of performance: A systematic review

The purpose of this systematic review article is to compile previous research on the needs of injured athletes during the rehabilitation period and their motivation to return to sports.

Responsible researcher

Ulrika Tranaeus

Project period

2022–2023

From risk to return, a consensus project

This systematic review article aims to compile previous research on the needs of injured athletes during rehabilitation and their motivation to return to sport. This project aims to summarize the research on psychological aspects of risk factors for injuries, rehabilitation needs, and criteria for return to sports. This article should be used in training coaches, naprapaths, and physiotherapists and as information for coaches and medical teams in sports.

Responsible researcher

Ulrika Tranaeus

Project period

2022–2025

Anabolic potential of skeletal muscle in healthy ageing

The project examines the growth capacity of the muscles in healthy older (70+) individuals compared to healthy young individuals.

Responsible researcher

William Apró

Project period

2017–2023

Fiber type specific regulation of protein synthesis in young and elderly muscle

The project investigates the molecular mechanisms that control protein synthesis in type I and type II muscle fibers in young and elderly healthy individuals.

Responsible researcher

William Apró

Project period

Project period

2020–2023

Muscle protein breakdown and the role of glycogen availability and amino acid supplementation

The project investigates the molecular mechanisms that control muscle protein breakdown and how these are affected by high or low glycogen availability and amino acid intake.

Responsible researcher

William Apró

Project period

2018–2023

Fiber type specific cell-signalling responses to energy and nutrient availability

The project investigates the cellular signaling cascades that regulate protein turnover in type I and type II fibers and how these are affected by high or low glycogen availability and amino acid intake.

Responsible researcher

William Apró

Project period

2020–2024

Anabolic resistance in age-related muscle loss (sarcopenia) and obesity

The project tries to clarify the molecular mechanisms behind reduced muscle-building capacity (anabolic resistance) in sarcopenia and obesity.

Responsible researcher

William Apró

Project period

2022–2026


Towards an evidence-based and fair classification system for athletes with Cerebral Palsy

The project aims to develop and evaluate an instrument for measuring arm function in athletes with coordination impairment. The results can then be used in creating a test battery for classifying athletes with impaired coordination, such as athletes with Cerebral Palsy.

Responsible researcher

William Apró

Project period

2022–2026

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Last modified:19 Sep 2024