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  2. Oscar Horwath

Oscar Horwath

Doktorand i idrottsvetenskap

Oscar Horwath
E-post oscar.horwath@gih.se
Telefon 08-120 53 845
Adress Box 5626, 114 86 Stockholm
Besöksadress Lidingövägen 1
Rum 1223
VCard
  • Akademisk titel

    Magisterexamen i biomedicin, Masterexamen i fysiologi och medicin

  • Tillhör

    Institutionen för fysiologi, nutrition och biomekanik

  • Kompetensprofil

    Fysiologi, Träningslära

  • Forskningsintressen

    My research interests largely revolve around cellular and molecular mechanisms that control skeletal muscle mass and how these are influenced by factors such as age, hormonal status, oxygen- and energy availability, exercise, and nutrition.

    In my PhD-project, using both in vitro and in vivo approaches, I have focused on the underlying causes of anabolic resistance, i.e., impaired sensitivity to exercise and nutrition, within the context of sarcopenia and obesity. My work improves the molecular understanding of how ageing and obesity impact skeletal muscle adaptability, which may facilitate the development of new treatments to combat muscle wasting in elderly populations.  

    Current projects

    1. The role of obesity in age-related anabolic resistance.
    2. The effect of testosterone administration on skeletal muscle in young women.
    3. The role of glycogen availability in autophagy signaling and adaptation to resistance exercise.
    4. The role of oxygen levels on the early satellite cell response to resistance exercise.

    Representative publications 

    • Fiber type-specific hypertrophy and increased capillarization in skeletal muscle following testosterone administration in young women. Horwath O, Apró W, Moberg M, Godhe M, Helge T, Ekblom M, Hirschberg AL, Ekblom B. J Appl Physiol (1985). 2020 May 1;128(5):1240-1250. doi: 10.1152/japplphysiol.00893.2019. Epub 2020 Mar 19.
    • Enhanced Skeletal Muscle Oxidative Capacity and Capillary-to-Fiber Ratio Following Moderately Increased Testosterone Exposure in Young Healthy Women. Cardinale DA, Horwath O, Elings-Knutsson J, Helge T, Godhe M, Bermon S, Moberg M, Flockhart M, Larsen FJ, Hirschberg AL, Ekblom B. Front Physiol. 2020 Dec 3;11:585490. doi: 10.3389/fphys.2020.585490. eCollection 2020.
    • Influence of sex and fiber type on the satellite cell pool in human skeletal muscle. Horwath O, Moberg M, Larsen FJ, Philp A, Apró W, Ekblom B. Scand J Med Sci Sports. 2021 Feb;31(2):303-312. doi: 10.1111/sms.13848. Epub 2020 Oct 20.

Senaste publikationer (DiVA)

Sida 1 av 3 (Totalt antal hämtade artiklar: 13)

 Författare Titel År URL
Horwath, Oscar
Moberg, Marcus
Hirschberg, Angelica Lindén
Ekblom, Björn
Apro, William
Molecular Regulators of Muscle Mass and Mitochondrial Remodeling Are Not Influenced by Testosterone Administration in Young Women. 2022 Fulltext
Blackwood, Sarah J
Horwath, Oscar
Moberg, Marcus
Pontén, Marjan
Apro, William
Ekblom, Maria
Larsen, Filip J
Katz, Abram
Extreme Variations in Muscle Fiber Composition Enable Detection of Insulin Resistance and Excessive Insulin Secretion. 2022 -
Moberg, Marcus
Apro, William
Horwath, Oscar
van Hall, Gerrit
Blackwood, Sarah J
Katz, Abram
Acute normobaric hypoxia blunts contraction-mediated mTORC1- and JNK-signaling in human skeletal muscle. 2022 Fulltext
Jonsson, William O
Ponette, Jonathan
Horwath, Oscar
Rydenstam, Tomas
Söderlund, Karin
Ekblom, Björn
Azzolini, Michele
Ruas, Jorge L
Blomstrand, Eva
Changes in plasma concentration of kynurenine following intake of branched-chain amino acids are not caused by alterations in muscle kynurenine metabolism. 2022 Fulltext
Davids, Charlie J
Næss, Tore C
Moen, Maria
Cumming, Kristoffer Toldnes
Horwath, Oscar
Psilander, Niklas
Ekblom, Björn
Coombes, Jeff S
Peake, Jonathan M
Raastad, Truls
Roberts, Llion Arwyn
Acute cellular and molecular responses and chronic adaptations to low-load blood flow restriction and high-load resistance exercise in trained individuals. 2021 -
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Se Oscar Horwaths publikationer i DiVA

  • Senast uppdaterad av: Jin Lavesson 2021-09-10

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08-120 537 00  

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