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You are here: Startpage Research Performance and Training Unit

Performance and Training Unit

Research area profiles

Muscle Metabolism & Biochemistry (Eva Blomstrand)

Skeletal muscle is a highly adaptive tissue responding to varying forms of acute and chronic exercise loading as well as dietary factors that induce specific intracellular signaling cascades involved in muscle protein anabolism and catabolism. Areas of research include the effect of combined endurance and strength training on AMPK-dependent inhibition of mTORC1 signaling, and gene and protein expression in the regulation of muscle hypertrophy and mitochondrial biogenesis. Our recent findings in this area demonstrate that signaling of muscle growth through the mTORC1-S6K1 axis after heavy resistance exercise is not inhibited by subsequent endurance exercise. Markers for protein catabolism are differently influenced by the two modes of exercise, however elevation in AMPK activity does not inhibit mTOR signaling after subsequent resistance exercise. Recent studies include the investigation of peroxisome proliferator-activated receptor gamma coactivator-1 alpha (PGC-1α) splice variant induction by resistance exercise, the specific stimulatory effect of dietary leucine on mTORC1 signalling and amino acid metabolism in connection with resistance exercise.

Sample Publications

Sida 9 av 20 (Totalt antal hämtade artiklar: 59)

 Författare Titel År URL
Wang, Li
Psilander, Niklas
Blomstrand, Eva
Mascher, Henrik
Sahlin, Kent
Resistance exercise enhances the molecular signaling of mitochondrial biogenesis induced by endurance exercise in human skeletal muscle. 2011 -
Mascher, Henrik
Ekblom, Björn
Rooyackers, Olav
Blomstrand, Eva
Enhanced rates of muscle protein synthesis and elevated mTOR signalling following endurance exercise in human subjects. 2011 -
Blomstrand, Eva
Krustrup, Peter
Søndergaard, Hans
Rådegran, Göran
Calbet, José A L
Saltin, Bengt
Exercise training induces similar elevations in the activity of oxoglutarate dehydrogenase and peak oxygen uptake in the human quadriceps muscle. 2011 -
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Biological Profile and Exercise Performance (Mikael Mattsson)

There is evidence for the contribution of genetic differences in training responsiveness as a factor in sport performance. Whole exome and genome sequencing and omics profiling offer the possibility to profile individual genetic makeup that may impact the tolerance, biological effects, and performance expected from training. Athletic personal omics profiling can facilitate monitoring over time and of different training approaches integrating biological information with change in physiological states (e.g., activity intensity, duration, response to training or performance level). This includes proteomic, transcriptomic, and metabolomic analyses during a period of training or recovery. This research approach is being undertaken in studies in competitive athletes in a variety of sports, including the effects of unilateral versus bilateral complex training combined with high intensity interval training on the development of strength, power and performance for elite male and female handball players. A similar approach is being undertaken in studies examining the response to prolonged physical exertion in military personnel.

Selected Publications

Sida 9 av 17 (Totalt antal hämtade artiklar: 51)

 Författare Titel År URL
Borgenvik, Marcus
Nordin, Marie
Mattsson, C. Mikael
Enqvist, Jonas K.
Blomstrand, Eva
Ekblom, Björn
Alterations in amino acid concentrations in the plasma and muscle in human subjects during 24 h of simulated adventure racing 2012 -
Björkman, Frida
Mattsson, C. Mikael
Hur farlig är multisport? 2011 -
Mattsson, C. Mikael
Wichardt, Emma
NSAID inom multisport 2011 -
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Applied Sports Physiology (Hans Rosdahl & Johnny Nilsson)

GIH has a rich tradition in sport physiology research and has led the field in establishment of gold-standard methods for measurement of oxidative metabolism in sport-specific events such as cross-country skiing and kayaking. Metabolic measurements coupled with kinematic, kinetic and electromyographic methods have been developed to examine components of performance enhancement in elite athletes. Development and validation of new ergometer technology and measurement software continues in close collaboration with Monark AB and Oxycon Mobile in combination with state-of-the art applications to field-monitoring of training and performance in rowing kayaking and skiing. Extending from this foundation, a central area of research is focused on the physiology of upper body sport performance, merging GIH's tradition and expertise in cardiovascular and muscle physiology.

Selected Publications

Sida 9 av 12 (Totalt antal hämtade artiklar: 35)

 Författare Titel År URL
Rosdahl, Hans
Hamrin, Kerstin
Ungerstedt, Urban
Henriksson, Jan
A microdialysis method for the in situ investigation of the action of large peptide molecules in human skeletal muscle 2000 -
Rosdahl, Hans
Studier av ämnesomsättning och blodflöde i skelettmuskulatur och fettväv 1998 -
Rosdahl, Hans
Hamrin, Kerstin
Ungerstedt, Urban
Henriksson, Jan
Metabolite levels in human skeletal muscle and adipose tissue studied with microdialysis at low perfusion flow. 1998 -
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Biomechanics (Toni Arndt)

GIH scientists have unique expertise in methods to study neuromuscular function and musculoskeletal biomechanical factors in sport performance and training. Application areas in advanced musculoskeletal biomechanics entail analysis of loading and behavior of specific anatomical structures during controlled physical activity. A specific focus of biomechanics research at GIH is the study of the muscle-tendon complex during different forms of loading exercise. Tendons and aponeuroses transmit forces from contracting muscles to bone, but these load-bearing tissues also act as biological springs, storing and releasing elastic energy. This elasticity enables tendons to fulfil a number of functions related to the mechanical efficiency and effectiveness of animal and human movement. Ongoing research projects include application of ultrasound-based methods coupled with force measures to quantify tendon mechanical properties in vivo during exercise performance. In partnership with Monark AB, cutting-edge research is also focused on the biomechanics of the lower extremity to develop world leading bicycle ergometers to optimize training for athletes. Developments within sensor technology, GPS systems and computer availability and performance have facilitated widespread interest in such monitoring. Specialized ergometry performance protocols and in-crank measurement of 3-dimensional forces to measure and visualize the effectiveness of the pedal cycle are being developed for aerobic endurance performance assessment.

Sample Publications

Sida 9 av 21 (Totalt antal hämtade artiklar: 61)

 Författare Titel År URL
Rosén, Johanna S
Arndt, Anton
Goosey-Tolfrey, Victoria L
Mason, Barry S
Hutchinson, Michael J
Tarassova, Olga
Bjerkefors, Anna
The impact of impairment on kinematic and kinetic variables in Va'a paddling 2019 Fulltext
Dias, Caroline Pieta
Freire, Bruno
Goulart, Natália Batista Albuquerque
Dias De Castro, Camila
Lemos, Fernando De Aguiar
Becker, Jefferson
Arndt, Anton
Vaz, Marco Aurélio
Impaired mechanical properties of Achilles tendon in spastic stroke survivors 2019 -
Sandamas, Paul
Gutierrez-Farewik, Elena M
Arndt, Anton
The effect of a reduced first step width on starting block and first stance power and impulses during an athletic sprint start. 2019 Fulltext
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Motor Control (Maria Ekblom)

The study of brain function in motor activation is of high interest for sport performance. A primary focus of research in motor control in sport performance at GIH is on central neural mechanisms involved in activation of motor units and measurement of intracortical facilitation and inhibition. An additional area of research is to examine the interplay between muscle and cortex mechanisms involved in of fatigue and the link between brain and muscle measures of oxygenation. Applying various modes of muscle activation, our research group also investigates the mechanisms by which the nervous system regulates muscle activation in the upper and lower limbs of sedentary and resistance trained individuals. Ongoing projects include the measurement of V-waves and MEPs in limbs and examining how short interval intracortical inhibition in the upper limbs is regulated with increased muscle activation.

Sample Publications

Sida 9 av 21 (Totalt antal hämtade artiklar: 62)

 Författare Titel År URL
Hirschberg, Angelica Lindén
Elings Knutsson, Jona
Helge, Torbjörn
Godhe, Manne
Ekblom, Maria
Bermon, Stephane
Ekblom, Björn
Effects of moderately increased testosterone concentration on physical performance in young women 2020 Fulltext
Gago, Paulo
Zoellner, Anja
Cezar, Julio
Ekblom, Maria M
Post Activation Potentiation and Concentric Contraction Performance 2020 -
Ekblom, Maria
Ekblom, Örjan
Börjesson, Mats
Bergström, Göran
Jern, Christina
Wallin, Anders
Device-Measured Sedentary Behavior, Physical Activity and Aerobic Fitness Are Independent Correlates of Cognitive Performance in Healthy Middle-Aged Adults-Results from the SCAPIS Pilot Study. 2019 Fulltext
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Sport Psychology (Sanna Nordin-Bates)

Research in the psychology of sport performance at GIH includes the investigation of psychological correlates of adherence, maturation and physical factors relating to dance performance. Integration of psychological, physical and enviromental factors reveal that greater levels of harmonious passion predict greater likelihood of adherence to dance programs, and greater ego-involving motivational climate perceptions predict less likelihood of adherence in young talented dancers. Other research findings indicate that perfectionistic concerns may color perceptions of training/performing environments. They also suggest that perceptions of a task-involving climate in training/performing environments may encourage striving for excellence and perfection without promoting excessive concerns regarding their attainment. Further research includes examination of applied perspectives on perfectionism and creativity in elite dancers, burnout and motivation in dance, teacher perceptions of dancer talent, and predictive indices of disordered eating. An extended area of research is directed towards promoting adolescent mental health in the school environment including the effect of dance participation.

Sample Publications

Sida 9 av 15 (Totalt antal hämtade artiklar: 45)

 Författare Titel År URL
Nordin-Bates, Sanna M
Cumming, Jennifer
Sharp, Lucinda
Aways, Danielle
Imagining yourself dancing to perfection? 2011 -
Nordin-Bates, Sanna M
Walker, Imogen J
Baker, Jo
Garner, Jocelyn
Hardy, Cinzia
Irvine, Sarah
Jola, Corinne
Laws, Helen
Blevins, Peta
Injury, imagery, and self-esteem in dance 2011 -
Norfield, Jennie
Nordin-Bates, Sanna M
How community dance leads to positive outcomes 2011 -
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  • Content Manager: David Lundström
  • Last modified by: Karin Jäppinen 2022-06-14

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08-120 537 00  

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