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You are here: Startpage Research Performance and Training Unit

Performance and Training Unit

Research area profiles

Muscle Metabolism & Biochemistry (Eva Blomstrand)

Skeletal muscle is a highly adaptive tissue responding to varying forms of acute and chronic exercise loading as well as dietary factors that induce specific intracellular signaling cascades involved in muscle protein anabolism and catabolism. Areas of research include the effect of combined endurance and strength training on AMPK-dependent inhibition of mTORC1 signaling, and gene and protein expression in the regulation of muscle hypertrophy and mitochondrial biogenesis. Our recent findings in this area demonstrate that signaling of muscle growth through the mTORC1-S6K1 axis after heavy resistance exercise is not inhibited by subsequent endurance exercise. Markers for protein catabolism are differently influenced by the two modes of exercise, however elevation in AMPK activity does not inhibit mTOR signaling after subsequent resistance exercise. Recent studies include the investigation of peroxisome proliferator-activated receptor gamma coactivator-1 alpha (PGC-1α) splice variant induction by resistance exercise, the specific stimulatory effect of dietary leucine on mTORC1 signalling and amino acid metabolism in connection with resistance exercise.

Sample Publications

Sida 6 av 20 (Totalt antal hämtade artiklar: 59)

 Författare Titel År URL
Nybo, Lars
Nielsen, Bodil
Blomstrand, Eva
Moller, Kirsten
Secher, Niels
Neurohumoral responses during prolonged exercise in humans. 2003 -
Karlsson, Håkan K R
Nilsson, Per-Anders
Nilsson, Johnny
Chibalin, Alexander V
Zierath, Juleen R
Blomstrand, Eva
Branched-chain amino acids increase p70S6k phosphorylation in human skeletal muscle after resistance exercise. 2004 -
Blomstrand, Eva
Møller, K
Secher, N H
Nybo, L
Effect of carbohydrate ingestion on brain exchange of amino acids during sustained exercise in human subjects. 2005 -
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Biological Profile and Exercise Performance (Mikael Mattsson)

There is evidence for the contribution of genetic differences in training responsiveness as a factor in sport performance. Whole exome and genome sequencing and omics profiling offer the possibility to profile individual genetic makeup that may impact the tolerance, biological effects, and performance expected from training. Athletic personal omics profiling can facilitate monitoring over time and of different training approaches integrating biological information with change in physiological states (e.g., activity intensity, duration, response to training or performance level). This includes proteomic, transcriptomic, and metabolomic analyses during a period of training or recovery. This research approach is being undertaken in studies in competitive athletes in a variety of sports, including the effects of unilateral versus bilateral complex training combined with high intensity interval training on the development of strength, power and performance for elite male and female handball players. A similar approach is being undertaken in studies examining the response to prolonged physical exertion in military personnel.

Selected Publications

Sida 6 av 17 (Totalt antal hämtade artiklar: 51)

 Författare Titel År URL
Wallberg, Linnea
Mattsson, C. Mikael
Enqvist, Jonas K.
Ekblom, Björn
Plasma IL-6 concentration during ultra-endurance exercise 2011 -
Wichardt, Emma
Mattsson, C. Mikael
Ekblom, Björn
Henriksson-Larsén, Karin
Rhabdomyolysis/myoglobinemia and NSAID during 48-hours ultra-endurance exercise (adventure racing) 2011 -
Mattsson, C. Mikael
Ståhlberg, Marcus
Larsen, Filip
Braunschweig, Frieder
Ekblom, Björn
Late cardiovascular drift observable during ultra endurance exercise. 2011 -
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Applied Sports Physiology (Hans Rosdahl & Johnny Nilsson)

GIH has a rich tradition in sport physiology research and has led the field in establishment of gold-standard methods for measurement of oxidative metabolism in sport-specific events such as cross-country skiing and kayaking. Metabolic measurements coupled with kinematic, kinetic and electromyographic methods have been developed to examine components of performance enhancement in elite athletes. Development and validation of new ergometer technology and measurement software continues in close collaboration with Monark AB and Oxycon Mobile in combination with state-of-the art applications to field-monitoring of training and performance in rowing kayaking and skiing. Extending from this foundation, a central area of research is focused on the physiology of upper body sport performance, merging GIH's tradition and expertise in cardiovascular and muscle physiology.

Selected Publications

Sida 6 av 12 (Totalt antal hämtade artiklar: 35)

 Författare Titel År URL
Calbet, J A L
Holmberg, H-C
Rosdahl, Hans
van Hall, Gerrit
Jensen-Urstad, Mats
Saltin, Bengt
Why do arms extract less oxygen than legs during exercise? 2005 -
Schantz, Peter
Stigell, Erik
Dang, Phung
Salier-Eriksson, Jane
Rosdahl, Hans
Kan fysiskt aktiv arbetspendling bli en "folkrörelse"? 2006 Fulltext
Holmberg, H-C
Rosdahl, Hans
Svedenhag, J
Lung function, arterial saturation and oxygen uptake in elite cross country skiers 2007 -
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Biomechanics (Toni Arndt)

GIH scientists have unique expertise in methods to study neuromuscular function and musculoskeletal biomechanical factors in sport performance and training. Application areas in advanced musculoskeletal biomechanics entail analysis of loading and behavior of specific anatomical structures during controlled physical activity. A specific focus of biomechanics research at GIH is the study of the muscle-tendon complex during different forms of loading exercise. Tendons and aponeuroses transmit forces from contracting muscles to bone, but these load-bearing tissues also act as biological springs, storing and releasing elastic energy. This elasticity enables tendons to fulfil a number of functions related to the mechanical efficiency and effectiveness of animal and human movement. Ongoing research projects include application of ultrasound-based methods coupled with force measures to quantify tendon mechanical properties in vivo during exercise performance. In partnership with Monark AB, cutting-edge research is also focused on the biomechanics of the lower extremity to develop world leading bicycle ergometers to optimize training for athletes. Developments within sensor technology, GPS systems and computer availability and performance have facilitated widespread interest in such monitoring. Specialized ergometry performance protocols and in-crank measurement of 3-dimensional forces to measure and visualize the effectiveness of the pedal cycle are being developed for aerobic endurance performance assessment.

Sample Publications

Sida 6 av 21 (Totalt antal hämtade artiklar: 61)

 Författare Titel År URL
Seynnes, Olivier R
Bojsen-Møller, Jens
Albracht, Kirsten
Arndt, Anton
Cronin, Neil J
Finni, Taija
Magnusson, S Peter
Ultrasound-Based Testing Of Tendon Mechanical Properties 2015 -
Begon, Mickaël
Dal Maso, Fabien
Arndt, Anton
Monnet, Tony
Can optimal marker weightings improve thoracohumeral kinematics accuracy? 2015 -
Dal Maso, Fabien
Raison, Maxime
Lundberg, Arne
Arndt, Anton
Allard, Paul
Begon, Mickaël
Glenohumeral translations during range-of-motion movements, activities of daily living, and sports activities in healthy participants. 2015 Fulltext
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Motor Control (Maria Ekblom)

The study of brain function in motor activation is of high interest for sport performance. A primary focus of research in motor control in sport performance at GIH is on central neural mechanisms involved in activation of motor units and measurement of intracortical facilitation and inhibition. An additional area of research is to examine the interplay between muscle and cortex mechanisms involved in of fatigue and the link between brain and muscle measures of oxygenation. Applying various modes of muscle activation, our research group also investigates the mechanisms by which the nervous system regulates muscle activation in the upper and lower limbs of sedentary and resistance trained individuals. Ongoing projects include the measurement of V-waves and MEPs in limbs and examining how short interval intracortical inhibition in the upper limbs is regulated with increased muscle activation.

Sample Publications

Sida 6 av 21 (Totalt antal hämtade artiklar: 62)

 Författare Titel År URL
Gago, Paulo
Marques, Mário C
Marinho, Daniel A
Ekblom, Maria M
Passive Muscle Length Changes Affect Twitch Potentiation in Power Athletes. 2014 Fulltext
Gago, Paulo
Arndt, Anton
Tarassova, Olga
Ekblom, Maria M
Post activation potentiation can be induced without impairing tendon stiffness. 2014 -
Ekblom, Maria
Är du chef? Överraska mig! 2015 -
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Sport Psychology (Sanna Nordin-Bates)

Research in the psychology of sport performance at GIH includes the investigation of psychological correlates of adherence, maturation and physical factors relating to dance performance. Integration of psychological, physical and enviromental factors reveal that greater levels of harmonious passion predict greater likelihood of adherence to dance programs, and greater ego-involving motivational climate perceptions predict less likelihood of adherence in young talented dancers. Other research findings indicate that perfectionistic concerns may color perceptions of training/performing environments. They also suggest that perceptions of a task-involving climate in training/performing environments may encourage striving for excellence and perfection without promoting excessive concerns regarding their attainment. Further research includes examination of applied perspectives on perfectionism and creativity in elite dancers, burnout and motivation in dance, teacher perceptions of dancer talent, and predictive indices of disordered eating. An extended area of research is directed towards promoting adolescent mental health in the school environment including the effect of dance participation.

Sample Publications

Sida 6 av 15 (Totalt antal hämtade artiklar: 45)

 Författare Titel År URL
Nordin-Bates, Sanna M
Walker, Imogen J
Baker, Jo
Garner, Jocelyn
Hardy, Cinzia
Irvine, Sarah
Jola, Corinne
Laws, Helen
Blevins, Peta
Injury, imagery, and self-esteem in dance 2011 -
Norfield, Jennie
Nordin-Bates, Sanna M
How community dance leads to positive outcomes 2011 -
Miulli, Michelle
Nordin-Bates, Sanna M
Motivational Climates 2011 -
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  • Content Manager: David Lundström
  • Last modified by: Karin Jäppinen 2022-06-14

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